There have been at least four natural deaths in our house, ranging from 1919 (elderly gentleman hit with the last wave of the Spanish Flu) through 1967. Doesn't bother me a bit. We all have to do it sometime and we have to be somewhere when we do. I'd much rather be at home when my time comes. At least three of the four had their wake in the living room. That's how the older generations did it. I can remember an aunt of mine who passed away in 1984 was waked in her living room.
The house next door to us is another story. It has been empty for several years and according to one of the neighbors, the previous owner's son was severely mentally ill and took the top of his head off with a 12 gauge in there. This happened in the early 1990s. It may be all psychological, but no one in the neighborhood likes that house and people have had some strange experiences there. A neighborhood handyman who was working on it last year told me that house made a believer out of him. He said he would hear sounds of someone walking upstairs, experienced things moving on their own, doors slamming shut, etc. The family that owns it still maintains it, but they spend as little time as possible there when they show up to take care of something. If anyone ever moves in there again, I will tell them that I highly recommend having a priest bless the place before they get settled in.
As for a house that used to be a funeral home, it wouldn't bother me. If I were a lost soul still lingering on this Earth, I think a funeral home is the last place I would want to haunt. I'd be more concerned about hazardous items like contaminated needles and scalpels that had been improperly disposed of than spirits!